the generation of bradykinin at the inflammatory site via depletion of the plasma kallikrein system, as well as limiting the formation of fibrin by reduction of clotting cascade intermediates. Bromelain has also been shown to stimulate the conversion of plasminogen to plasmin, resulting in
increased fibrinolysis. These anti-inflammatory effects make bromelain an effective treatment tool for musculoskeletal inflammation of all types – from tendinitis to arthritis to myofascial pain.
Studies indicate the effects of orally administered bromelain include the reduction of edema, bruising, pain, and healing time following trauma and surgical procedures. The pain reduction effects of bromelain are probably related to its anti-inflammatory properties rather than direct analgesic effects. In one clinical study, patients with long bone fractures administered a proteolytic enzyme combination containing bromelain had less post-operative swelling and consumed fewer analgesics compared to patients given placebo. Bromelain has also been shown to reduce swelling,
bruising, pain, and healing time in patients following dental surgeries. In a double-blind study of post-dental surgery patients, bromelain was found to decrease swelling to 3.8 days compared with seven days in patients given placebo. In addition, duration of pain was reduced to five days in
the treatment group compared to eight days in the placebo group. In one trial, bromelain was reported to positively influence swelling, pain, and tenderness in patients with blunt injuries to the musculoskeletal system.
Aside from its documented anti-inflammatory activity, bromelain is of interest to plastic surgeons because of its ability to increase resorption rate of hematomas. Oral bromelain, given at the time of hematoma and for seven days thereafter, resulted in significantly faster hematoma resolution in
the treatment group than in controls.
|Supplement Facts||Dosage:2 capsules tid
SPECIAL NOTE: This product may be contraindicated in an individual allergic to pineapple. This product may be contraindicated in an individual with peptic ulcers.
|Name||Thorne Research, M.F. Bromelain 60 capsules|
|Product Type||Corn Free, Dairy Free, Egg Free, Gluten Free, Hypoallergenic, Wheat Free, Yeast Free|