Trauma, infection, starvation, chemotherapy, and other stressors are all associated with a derangement of normal intestinal permeability. In numerous animal studies of experimentally induced intestinal hyperpermeability, the addition of glutamine improved gut barrier function as well as immune activity in the gut. Impaired gut permeability allows for large protein molecules to diffuse across the damaged mucosa and enter the bloodstream. The body identifies these proteins as foreign and mounts an immune reaction against them, resulting in food allergies.
Under certain pathological circumstances the body’s tissues need more glutamine than the amount supplied by diet and synthesis. In times of metabolic stress, glutamine is released into circulation, where it is transported to the tissue in need. Intracellular skeletal muscle glutamine concentration is affected by various insults, including injury, sepsis, prolonged stress, starvation, and the use of glucocorticoids. Glutamine is therefore classified as a conditionally essential amino acid. Research demonstrates glutamine supplementation may benefit surgery and trauma patients. In
addition, evidence suggests supplemental glutamine may provide benefit for certain gastrointestinal conditions (Crohn’s disease, ulcerative colitis, irritable bowel syndrome, stomach ulcers, gastritis, and food allergies), wound healing, HIV patients, immune enhancement in endurance athletes, and prevention of complications associated with chemotherapy and radiation.
|Supplement Facts||Dosage:2 to 4 capsules bid
A woman who is pregnant or nursing, or who might become pregnant, should consult a health-care practitioner before using this product.
|Name||Thorne Research, L-Glutamine 90 capsules|
|Product Type||Corn Free, Dairy Free, Egg Free, Gluten Free, Hypoallergenic, Wheat Free, Yeast Free|