Thorne Research, CystePlus 500 mg 90 capsules


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    Product Description

    N-acetylcysteine (NAC) is the precursor of both the amino acid L-cysteine and reduced glutathione (GSH). Animal and human studies of NAC have shown it to be a powerful antioxidant and a therapeutic agent for heavy metal toxicity and other diseases characterized by free radical, oxidative damage. As a source of sulfhydryl groups, NAC stimulates glutathione synthesis, enhances glutathione-S-transferase activity, promotes liver detoxification by inhibiting xenobiotic biotransformation, and is a powerful nucleophile capable of scavenging free radicals. Historically the most prevalent and well-accepted use of NAC has been as an antidote for acetaminophen (Tylenol) poisoning. The resultant liver toxicity is due to an acetaminophen metabolite that depletes the hepatocytes of glutathione and causes hepatocellular damage and possibly even death. NAC administered intravenously or orally within 24 hours of overdose is effective at preventing liver toxicity; however, improvement is most notable if treatment is initiated within 8-10 hours of acetaminophen overdose. NAC has also been effective for poisoning by carbon tetrachloride, acrylonitriles, halothane, paraquat, acetaldehyde, coumarin, and interferon. In addition to its dramatic effects in liver poisoning, NAC is effective in promoting normal liver detoxification.

    Research suggests NAC is capable of enhancing T-cell immunity by stimulating T-cell colony formation, and blocking NF kappa B expression. In a double-blind, placebo-controlled trial, NAC was shown to positively impact CD4+ lymphocyte cell counts. NAC has application for respiratory ailments due to its mucolytic activity. NAC’s sulfhydryl group cleaves disulfide bonds in mucoproteins, causing mucus to be subsequently broken into smaller, less viscous units. NAC has been noted to decrease the viscoelasticity of nasal mucus and increase the mucociliary clearance rate by thinning of secretions, improving conditions such as bronchitis and flu. Several animal and human studies have explored NAC’s effectiveness as a therapeutic agent for various types of respiratory illness. While results vary, NAC administration has resulted in improved expectoration, with decreased cough severity and diaphragm fatigue. In a small study of 18 patients with fibrosing alveolitis – a condition characterized by severe oxidative stress and decreased glutathione levels – NAC 600 mg three times daily for 12 weeks resulted in improvement in pulmonary function and glutathione levels.

    Supplement Facts

    Supplement Facts Dosage:1 capsule tid with meals
    Each Capsule Contains DV%
    500 mg
    *Daily Value (DV) not established
    SA560/ 90

    A woman who is pregnant or nursing, or who might become pregnant, should consult a health-care practitioner before using this product.

    Additional Information

    SKU TR-SA560
    Name Thorne Research, CystePlus 500 mg 90 capsules
    UPC 693749560029
    MPN SA560
    Brand Thorne Research
    Form Capsule
    Shipping Weight 0.1900
    Serving Size 1
    Product Type Corn Free, Dairy Free, Egg Free, Gluten Free, Hypoallergenic, Wheat Free, Yeast Free


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    Published by Robin on 2011-01-19 14:08:40
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