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Integrative Therapeutics, 7-Keto Lean 30 ultracaps SKU #: ITI-75163
Price: $45.00
On Sale: $42.75
Product Specs
| Form |
UltraCap |
| Servings |
30 |
| Serving Size |
1 |
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Benefits
| • |
Safe, natural, significant weight loss.† |
| • |
Not an appetite suppressant or stimulant; won't keep you awake at night.† |
| • |
Nutrients to supports thyroid function and metabolism.† |
Key Features
| • |
Contains clinically studied ingredient, 7-Keto, an improved and safe form of DHEA.† |
Forget about crash diets and artificial stimulants - this supplement is clinically shown to burn fat and promote weight loss when used in conjunction with a healthy diet and exercise program.† This improved metabolite of DHEA is combined with 7 other ingredients, including L-tyrosine and iodine to support thyroid function and metabolism.†
RecommendationsTake 1 or 2 UltraCaps daily.
| Serving Size: 1 UltraCap |
Amount/Serving |
%DV |
|
| Iodine (from potassium iodide) |
100 |
mcg |
67% |
|
| Copper (as copper gluconate) |
500 |
mcg |
25% |
|
| Manganese (as manganese Krebs cycle chelates)** |
500 |
mcg |
25% |
|
| Asparagus (Asparagus officinalis) Rhizome Extract |
100 |
mg |
* |
 |
standardized to contain 4% asparagosides |
|
|
| L-Tyrosine |
100 |
mg |
* |
|
| 7-keto DHEA Acetate (7-KETO® brand) |
100 |
mg |
* |
|
| Choline Bitartrate |
50 |
mg |
* |
|
| Inositol |
50 |
mg |
* |
|
| *Daily Value (DV) not established. |
Other Ingredientsvegetable capsule (modified cellulose), magnesium stearate, and silicon dioxide.Contains Nosugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring or preservatives. This product contains natural ingredients; color variations are normal.Notes **Chelated as citrate, fumarate, malate, succinate, and alpha ketoglutarate.
7-Keto is a registered trademark of Humanetics Corporation.
If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.
Integrative Therapeutics, 7-Keto Lean 30 ultracaps Reviews
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How Does It Work?:Both DHEA (dehydroepiandrosterone) and 7-keto DHEA are associated with a variety of essential human functions, most notably immune system support and memory enhancement.* In the body, DHEA can convert into various metabolites, including 7-keto DHEA and steroid hormones, such as testosterone or the estrogens (estrone and estradiol).(7) 7-keto DHEA, on the other hand, does not convert to active testosterone and/or estrogen in the body.*(4)(5) Nor does it convert back to DHEA. In fact, this improved form of DHEA has no known adverse effects.*(4)(6)
Research has shown that 7-keto DHEA increases thermogenic enzyme activity, which is associated with heat generation.* An increase in thermogenic activity may enhance the body's basal metabolic rate, helping to promote weight loss without requiring significant alterations to caloric intake or activity levels. *(5)(8)(10) Additionally, 7-keto DHEA has been shown to support healthy thyroid function.*(11) The thyroid gland, which plays a permissive role in adaptive heat production, is also intricately involved in maintaining optimal metabolic rate. (12)(13)
An eight-week clinical trial found that supplementation with 7-keto DHEA (200 mg/day), in conjunction with diet and exercise, significantly reduced both body weight and body fat.* 7-keto DHEA also supported healthy thyroid hormone (triiodothyronine or T3) levels, which may affect basal metabolic rate, further enhancing weight loss.*(11)
When combined with supportive nutrients, the effects of 7-keto DHEA can be even more pronounced. A recent placebo-controlled clinical study, examining the effectiveness of 7-Keto Lean in combination with a healthy diet and moderate exercise program, found the supplemented group lost 1.43 kg (or 3.15 lb) more than the placebo group over the course of eight weeks.* On average, the 7-Keto Lean group lost a total of 2.15 kg (or 4.74 lb), whereas the placebo group, lost only 0.72 kg (1.59 lb). The body mass index (BMI), a measure of body fat based on height and weight, was also significantly decreased, confirming the weight loss was primarily due to loss of body fat rather than loss of muscle tissue.*
The following chart summarizes the benefits of each of the ingredients in 7-Keto Lean:*
| Ingredient |
Benefit |
| 7-keto DHEA Acetate |
A safe and improved form of DHEA. Clinically shown to enhance weight loss and reduce body fat by supporting healthy thyroid function, thyroid hormone biosynthesis, and fat metabolism.((11) Also increases thermogenic enzyme activity.*(5)(8-10) |
| L-Tyrosine |
An essential nutrient required for thyroid hormone formation.((12)(13) |
| Asparagus Extract |
A potent metabolic detoxifier that supports healthy fluid balance.*(14) |
| Choline |
A nutrient involved in many important metabolic functions, including fat transport and metabolism.(15)(16) |
| Inositol |
Another nutrient which promotes the transport and metabolism of fat.(17) |
| Copper |
An essential trace mineral and cofactor of enzymes involved in carbohydrate and fat metabolism.(18) |
| Manganese |
An essential mineral required for healthy thyroid hormone metabolism.*(19)(20) |
| Iodine |
Another essential nutrient found in high concentrations in the thyroid gland. Required for the synthesis of thyroid hormones, which are important in regulating cellular metabolic rate.*(21)(12)(13) |
Conclusion The ingredients 7-Keto Lean work synergistically to support healthy thyroid function and enhance metabolism.* When used in conjunction with a sensible diet and regular exercise, 7-Keto Lean can accelerate the loss of body fat to promote weight loss, while maintaining muscle tissue integrity.*
Recommendations:One or two UltraCaps™ daily.Precautions:If you are pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use. 7-keto DHEA does not convert to active testosterone and/or estrogen4,5 and does not have known adverse effects.(4)(6) How Is It Supplied?:
Storage Recommendations:Store at controlled room temperature, 59° to 86°F (15° – 30°C).References:
- Parker LN. Adrenal Androgens in Clinical Medicine. San Diego, Calif: Academic Press, Inc.; 1989:14.
- Marenich LP. Excretion of testosterone, epitestosterone, androstenedione and 7-keto-dehydroepiandrosterone in healthy men of different ages. Probl Endokrinol. 1979;25:28-31.
- Zenk JL, Helmer TR, Kassen LJ, Kuskowski MA. The effect of 7-KETO NaturaleanTM on weight loss: a randomized, double-blind, placebo-controlled trial. Curr Ther Res. 2002 Apr;63(4):263-72.
- Weeks C, Lardy H, Henwood S. Preclinical toxicology evaluation of 3-acetyl-7-oxo-dehydroepiandrosterone (7-keto-DHEA). The FASEB J. 1998;12:A764. Proceedings Abstract (4428).
- Lardy H, Partridge B, Kneer N, et al. Ergosteroids: induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone. Proc Natl Acad Sci U S A. 1995;92:6617-6619. Proceedings Abstract.
- Davison MH, Weeks C, Lardy H, et al. Safety and endocrine effects of 3-acetyl-7-oxo-DHEA (7-keto-DHEA). The FASEB J. 1998;12:A764.
- Fleming T, ed. DHEA (dehydroepiandrosterone). In: PDR® for Nutritional Supplements. Montvale, NJ: Medical Economics Company; 2001: 127-131.
- Su CY, Lardy H. Induction of hepatic mitochondrial glycerophosphate dehydrogenase in rats by dehydroepiandrosterone. J Biochem. 1991;110:207-213.
- Bobyleva V, Bellei M, Kneer N, et al. The effects of ergosteroid 7-oxo-dehydroepiandrosterone on mitochondrial membrane potential: possible relationship to thermogenesis. Arch Biochem Biophys. 1997:341:122-128.
- Lardy H, Reich IL. delta5-androstenes useful for promoting weight maintenance or weight loss and treatment process. 1996. United States Patent: 5506223.
- Colker CM, Torina GC, Swain MA, et al. Double-blind study evaluation the effects of exercise plus 3-acetyl-7-oxo-dehydroepiandrosterone on body composition and the endocrine system in overweight adults. J Exerc Physiol (online). 1999;2:1-2. Available at: http://www.css.edu/users/tboone2/asep/abstractROB.html.
- Johnson LR. ed. Thyroid gland. In: Essential Medical Physiology. 2nd ed. Philadelphia:Lippincott-Raven Publishers; 1998:521-535.
- McNabb FMA. Thyroid hormones, their activation, degradation and effects on metabolism. J Nutr. 1995;125:1773S-1776S.
- Fleming T, ed. Asparagus Officinalis. In: PDR® for Herbal Medicines. Montvale, NJ: Medical Economics Company;1998:673-675.
- Combs GF, ed. Choline. In: The Vitamins. Fundamental Aspects in Nutrition and Health. San Diego:Academic Press, Inc.; 1992:401.
- Shronts EP. Essential nature of choline with implications for total parenteral nutrition. J Am Diet Assoc. 1997;97:639-646,649.
- Combs GF, ed. Inositol. In: The Vitamins. Fundamental Aspects in Nutrition and Health. San Diego:Academic Press, Inc.; 1992:419.
- Linder MC. Copper. In: Ziegler EE, Filer LJ, Jr., ed. Present Knowledge in Nutrition. 7th ed. Washington, DC: International Life Sciences Institute; 1996:310.
- Eder K, Kralik A, Kirchgessner M. The effect of manganese supply on thyroid hormone metabolism in the offspring of manganese-depleted dams. Biol Trace Elem Res. 1996;55:137-145.
- Aihara K, Niahi Y, Hatano S, et al. Zinc, copper, manganese, and selenium metabolism in thyroid disease. Am J Clin Nutr. 1984;40:26-35.
- Marieb E. Minerals. In: Human Anatomy and Physiology. San Francisco, CA: Pearson Benjamin Cummings; 2004:9
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