Rooibos tea unfermented powder blend with Zembrin Sceletium Tortuosum extract. The proprietary and patented Zembrin extract used in Organic African Red Tea Sceletium Tortuosum (also known as Kanna, Channa, and Kougoed) safely supports a sense of alert serenity. It is traditionally used to relax the mind, reduce stress, and promote healthy sleep. Sceletium Tortuosum has been used for millennia and its use has been documented for 300 years.
Sceletium tortuosum is a succulent plant native to South Africa. The indigenous people have used the herb as a mood enhancer, relaxant, and empathogen for centuries. They have also used it for gastrointestinal and respiratory ailments, colic, and to help combat addictions to drugs and alcohol. The most common uses of sceletium tortuosum were to help with endurance and to clear the mind to help with thinking. It has also been used as an appetite suppressant.
Modern doctors, psychologists, and psychiatrists have been successful in using sceletium tortuosum for:
\xB7 Mood enhancement
\xB7 Lessen fatigue
\xB7 PMS stress reduction
\xB7 Increased energy and endurance
\xB7 Enhance cognitive abilities
\xB7 Improved mental focus and clarity
\xB7 Promotes restful sleep
\xB7 No severe adverse effects have been documented
The Zembrin extract contains mesembrine, mesembrenol, and tortuosamine which are the main alkaloids that interact with the brain's dopamine and serotonin receptors and causes the mood enhancement. The U.S. Patent Office confirmed it a serotonin re-uptake inhibitor (SRI) which regulates the most important neurotransmitter in the brain.
The Zembrin extract is a proprietary standardized Sceletium extract. A few of the unique properties are:
\xB7 has self-affirmed Generally Regarded As Safe (GRAS) status in USA.
\xB7 has been clinically studied for efficacy, with significant positive results.
\xB7 has been clinically studied for safety - the first clinical safety study on Sceletium.
\xB7 is patented, with granted patents and new patent applications.
\xB7 is the only Sceletium extract with published pharmacology.
\xB7 is manufactured at a certified EU-GMP manufacturer, the first standardized extract to have been made from Sceletium.
\xB7 is produced from HG&H\x92s own elite naturally occurring chemotype of Sceletium, the first large-scale commercial cultivation of a Sceletium chemotype.
\xB7 is the only Sceletium product to carry the logo of its indigenous beneficiaries - the South African San Council.
Zembrin is a standardized extract of cultivated elite plant material. Zembrin has recognized mechanisms of action involved in feelings of relaxation, calm and stress reduction. The activities have been demonstrated for the whole extract and also for the isolated key markers present in the extract, providing a rationale for the standardization to selected markers.
The quality and standardization of Zembrin is guaranteed by carefully controlled horticulture using proprietary seeds and vegetative cuttings of a select chemotype, cultivated to Global-GAP. Absolutely no wild crafting. The growing and harvesting on farms employs rural folk in these areas. Standard operating procedures are followed for the harvesting, washing, as well as for the method, duration and temperature of drying of the plant material. Key marker compounds are quantified in the raw material and extract on an ongoing basis to ensure the integrity of the phytochemical profile during production, and to determine shelf-life. Records are kept to ensure complete traceability from seed to extract.
In vitro, in vivo, and Phase-1 safety studies of Zembrin in healthy human volunteers have found no evidence of toxicity. A double-blind placebo-controlled Phase 1 clinical trial on two doses of Zembrin demonstrated good tolerability over the 3 months studied. There were no significant adverse events in the active group, and there were no differences between active and placebo groups in vital signs,